Simple clinical tests may predict severe oropharyngeal dysphagia in Parkinson's disease

✍ Scribed by Kuen Lam; Florence Kwai Yi Lam; Kwok Kwong Lau; Yiu Kay Chan; Elaine Yee Ling Kan; Jean Woo; Fat Kee Wong; Andrew Ko

• Publisher: John Wiley and Sons
• Year: 2007
• Tongue: English
• Weight: 58 KB
• Volume: 22
• Category: Article
• ISSN: 0885-3185
• DOI: 10.1002/mds.21362

✦ Synopsis

Abstract

Objective: To determine if simple screening tests can predict severe oropharyngeal dysphagia in subjects with Parkinson's disease. Methodology: Forty‐five subjects (26 females) of average age 75 (range: 65–94) who were classified as Modified Hoehn and Yahr stages 2 to 5 were enrolled. The presence of oropharyngeal dysphagia was assessed by a symptom questionnaire, 50 ml water swallowing test and videofluroscopic swallowing study. Results: Six of the subjects had severe oropharyngeal dysphagia in videofluroscopic swallowing study. Subsequent multivariate analysis showed that 3 factors could independently predict severe oropharyngeal dysphagia. These included higher Modified Hoehn and Yahr stage (P = 0.042), low Body mass index (P = 0.014), and increased difficulty in keeping food or drink in the mouth (P = 0.047). The regression model had a positive predictive power of 96% (sensitivity: 83.3%, specificity: 97.4%). Conclusion: A combination of 3 simple clinical parameters may be useful for screening for severe oropharyngeal dysphagia as shown radiologically in subjects with Parkinson's disease. © 2007 Movement Disorder Society