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Simple and sensitive HPLC method for determination of amrubicin and amrubicinol in human plasma: application to a clinical pharmacokinetic study

✍ Scribed by Reiko Ando; Yoshinori Makino; Tomohide Tamura; Noboru Yamamoto; Rena Nishigaki; Takehiro Kimura; Nobuaki Yokote; Hiroshi Yamamoto


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
312 KB
Volume
24
Category
Article
ISSN
0269-3879

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## Abstract Phenoprolamine hydrochloride is a novel compound that works against a variety of types of hypertension. The purpose of this study was to develop a simple and sensitive high‐performance liquid chromatographic method for quantitation of low phenoprolamine hydrochloride concentrations in h