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Simple and Highly Convenient Two-Step Practical Procedure for the Synthesis of Optically Pure Methyl D-erythro-2,3-Dihydroxybutanoate

✍ Scribed by S. M. Mahalingam; N. Sathyamurthi; I. S. Aidhen


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
59 KB
Volume
347
Category
Article
ISSN
1615-4150

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✦ Synopsis


A synthesis of enantiopure methyl d-erythro-2,3-dihydroxybutanoate has been realized using two simple and consecutive reactions on d-erythronolactone as the starting material. The two reactions are lactone ring opening with hydrobromic acid in methanol and subsequent reductive debromination.