Similarity of effects—experimental hyperthermia as a teratogen and maternal febrile illness associated with oromandibular and limb defects

Teratogen update: Gestational effects of

Teratogen update: Gestational effects of maternal hyperthermia due to febrile illnesses and resultant patterns of defects in humans

✍ Graham, John M.; Edwards, Matthew J.; Edwards, Marshall J. 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 475 KB 👁 1 views

Hyperthermia was the first teratogen in animals that was subsequently proven to be teratogenic in humans. Animal studies have demonstrated heat to be a significant cause for reproductive problems in a wide variety of mammals. These problems range from embryonic death and abortion to teratogenically