Similarity of binary mixed aqueous-organic solvents for capillary zone electrophoresis based on the ionic mobility of substituted benzoates evaluated by cluster analysis and information theory
✍ Scribed by Karim Sarmini; Gregor Reich; Ernst Kenndler
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 85 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1040-7685
No coin nor oath required. For personal study only.
✦ Synopsis
The similarity of solvents used for buffering background electrolytes in capillary zone electrophoresis is evaluated by two chemometric techniques: cluster analysis and information theory. The solvents are water and binary aqueous-organic mixtures of methanol, ethanol, 1-propanol, and acetonitrile, respectively, with concentrations up to 80% vrv of the organic constituent. The electrophoretic properties of the solvents are described by the actual mobilities of 26 aromatic anions, hydroxy-, methyl-, nitro-, and chloro-substituted benzoates. Cluster analysis results in two main clusters, the one consisting of the alcoholic systems, the other of water and the mixtures with acetonitrile. The information content of the single solvent systems ranges up to 4 bit for the acetonitrilic solvent. The similarity of the systems is evaluated by information theory from the loss of information content due to the correlation between the mobility data in the particular solvents.