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Simian virus 40, poliovaccines and human tumors: a review of recent developments

โœ Scribed by Carbone, Michele; Rizzo, Paola; Pass, Harvey I


Book ID
110060959
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
792 KB
Volume
15
Category
Article
ISSN
0950-9232

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## Abstract Serum antibodies are widely utilised as specific and sensitive markers of virus infections but they have been employed relatively infrequently in the investigation of simian virus 40 (SV40) as a human carcinogen. In the past few years, serological data have become available which allow

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Simian virus 40 (SV40), a monkey polyomavirus, was a contaminant of early poliovirus vaccines administered to millions of individuals in the 1950s and early 1960s. SV40 causes brain tumors in laboratory animals, and SV40 DNA sequences have been variably identified in human choroid plexus tumors and

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