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Simian virus 40 persistent infection in long-term immortalized human fibroblast cell lines

✍ Scribed by Cristina Morelli; Federica Barbisan; Laura Iaccheri; Mauro Tognon


Book ID
111739247
Publisher
Springer US
Year
2004
Tongue
English
Weight
478 KB
Volume
10
Category
Article
ISSN
1355-0284

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## Abstract Simian virus 40 large T antigen (SVLTAg) has been used to immortalize cells; however, the mechanism leading to immortalization is still unclear. We hypothesize that DNA mismatch repair (MMR) activity is important during SVLTAg‐induced immortalization. To test this hypothesis, we used th