Simian Virus 40 Induces Multiple S Phases with the Majority of Viral DNA Replication in the G2 and Second S Phase in CV-1 Cells

Okadaic acid induces appearance of the m

Okadaic acid induces appearance of the mitotic epitope MPM-2 in SV40-infected CV-1 cells with a >G2-phase DNA content

✍ Thomas D. Friedrich; Eiji Okubo; Judith Laffin; John M. Lehman 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 69 KB 👁 2 views

Simian virus 40 (SV40) infection of quiescent monkey kidney cells stimulates two successive rounds of cellular DNA synthesis without an intervening mitosis. This uncoupling of S phase and mitosis indicates that SV40 modulates pathways regulating the G2to-M phase transition. To examine the integrity