Prior to delivery to the patient, protein pharmaceuticals often come in contact with a variety of surfaces (e.g., syringes and stoppers), which are treated to facilitate processing or to inhibit protein binding. One such coating, silicone oil, has previously been implicated in the induction of prote
Silicone oil induced glaucoma: A review
β Scribed by Parul Ichhpujani; Anjana Jindal; L. Jay Katz
- Book ID
- 106098256
- Publisher
- Springer-Verlag
- Year
- 2009
- Tongue
- English
- Weight
- 425 KB
- Volume
- 247
- Category
- Article
- ISSN
- 0065-6100
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## Purpose: To evaluate the prevalence of glaucoma after pars plana vitrectomy with silicone oil injection and to determine the different clinical forms. ## Methods: Authors have carried out a retrospective longitudinal study on patients who underwent pars plana vitrectomy with silicone oil injec
## Purpose: We analyzed morphological changes in trabecular meshwork in glaucoma developing after intravitreal silicone oil injection with transmission electron microscopy (tem). ## Methods: Specimens obtained from 2 patients after surgical trabeculectomy were fixed in mcdowell fixative in one pa
Silicone oil, which is used as a lubricant or coating in devices such as syringes, needles and pharmaceutical containers, has been implicated in aggregation and particulation of proteins and antibodies. Aggregation of therapeutic protein products induced by silicone oil can pose a challenge to their