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Silicone microspheres for pH-controlled gastrointestinal drug delivery

โœ Scribed by V. Carelli; S. Coltelli; G. Di Colo; E. Nannipieri; M.F. Serafini


Book ID
118579436
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
305 KB
Volume
179
Category
Article
ISSN
0378-5173

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One of the most important inconveniences of the pH- and temperature-sensitive hydrogels is the loss of thermosensitivity when relatively large amounts of a pH-sensitive monomer are co-polymerized with N-isopropylacrylamide (NIPAAm). In order to overcome this drawback, we propose here a method to pre