✦ LIBER ✦
Silicon directed diastereo- and enantioselective mukaiyama michael tandem aldol condensation: a novel strategy for six membered ring cyclisation
✍ Scribed by BraJ B. Lohray; R. Zimbiniski
- Book ID
- 104221860
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- French
- Weight
- 236 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
Silicon directed diastereo-and enantioselective conjugate addition of enolsilanes to a$unsaturated ketones are reported which undergo subsequent intramolecular oyclization on treatment with aqueous HBF4 to furnish aldol adducts. Depending on the substltuents, the aldol adducts undergo dehydration to give substituted a&unsaturated cyclohexenones.