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Silica-supported synthesis of some 1,3,5-trisubstituted 2-pyrazolines under solvent-free and microwave irradiation conditions

โœ Scribed by Davood Azarifar; Behrooz Maleki


Publisher
Journal of Heterocyclic Chemistry
Year
2005
Tongue
English
Weight
38 KB
Volume
42
Category
Article
ISSN
0022-152X

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โœฆ Synopsis


A simple method for the synthesis of 2-pyrazolines is described which occurs on silica surface under solvent-free conditions within 110-180 sec using microwave irradiation. The results obtained indicate that the use of silica gel as a support in pyrazoline formation reactions can have a profound effect on reaction rates and yields and cause cleaner reaction conditions.


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