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Silica Sulfuric Acid-Catalyzed Reaction of 4-Hydroxyproline with 11H-Indeno[1,2-b]quinoxalin-11-one and Isatin Derivatives: A Novel Synthesis of New Pyrrole Compounds.

✍ Scribed by Javad Azizian; Ali Reza Karimi; Zahra Kazemizadeh; Ali A. Mohammadi; Mohammad R. Mohammadizadeh

Publisher: John Wiley and Sons
Year: 2005
Weight: 19 KB
Volume: 36
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200541112

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## Abstract A sequential one‐pot four‐component reaction for the efficient synthesis of novel 2′‐aminospiro[11__H__‐indeno[1,2‐__b__]quinoxaline‐11,4′‐[4__H__]pyran] derivatives **5** in the presence of AcONH~4~ as a neutral, inexpensive, and dually activating catalyst is described (__Scheme 1__).