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Silica sulfuric acid as an efficient and recoverable catalyst for the synthesis of trisubstituted imidazoles

✍ Scribed by Ahmad Shaabani; Abbas Rahmati

Book ID: 104056980
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 104 KB
Volume: 249
Category: Article
ISSN: 1381-1169
DOI: 10.1016/j.molcata.2006.01.006

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✦ Synopsis

Trisubstituted imidazoles have been synthesized in high yields in the presence of silica sulfuric acid as a catalyst. The reaction is carried out in water, a very green solvent, under reflux conditions. The reaction work-up is simple and the catalyst is easily separated from the products by filtration.

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