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Silica-lipid hybrid (SLH) microcapsules: A novel oral delivery system for poorly soluble drugs

✍ Scribed by Angel Tan; Spomenka Simovic; Andrew K. Davey; Thomas Rades; Clive A. Prestidge


Book ID
113692535
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
782 KB
Volume
134
Category
Article
ISSN
0168-3659

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The solution of a poorly water-soluble drug in a liquid lipid-surfactant mixture, which served as a microemulsion preconcentrate, was converted into a solid form by incorporating it in a solid polyethylene glycol (PEG) matrix. The solid microemulsion preconcentrates thus formed consisted of Capmul P