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Silencing the Metallothionein-2A Gene Induces Entosis in Adherent MCF-7 Breast Cancer Cells

✍ Scribed by Yiyang Lai; Daina Lim; Puay-Hoon Tan; Thomas King-Chor Leung; George Wai-Cheong Yip; Boon-Huat Bay


Book ID
101602825
Publisher
Wiley (John Wiley & Sons)
Year
2010
Tongue
English
Weight
479 KB
Volume
293
Category
Article
ISSN
1932-8486

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## Abstract Constitutive activation of M‐Ras has previously been reported to cause morphologic and growth transformation of murine cells, suggesting that M‐Ras plays a role in tumorigenesis. Cell transformation by M‐Ras correlated with weak activation of the Raf/MEK/ERK pathway, although contributi