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Silencing Pin1 suppresses the expression and bioactivity of MMP-9 through NF-κB in colorectal carcinoma SW480 cells

✍ Scribed by Li-yuan Qin; Mei-ning Li; Wen-juan Ren; Dong Zhang; Jian-lin Zhang; Yue-hong Zhang; Niu-liang Cheng


Book ID
107513274
Publisher
Springer-Verlag
Year
2010
Weight
492 KB
Volume
7
Category
Article
ISSN
1674-5361

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## Abstract Nuclear factor kappa B (NFκB) is a central participant in the metastasis and chemoresistance of colorectal cancer (CRC). However, it is not fully understood to what extent NFκB contributes to induction of the metastasis‐associated matrix metalloprotease‐9 (__MMP‐9__) gene and sensitivit