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Silencing of the type 1 insulin-like growth factor receptor (IGF1R) gene by RNA interference inhibits survival and enhances sensitivity of human prostate cancer to DNA damaging agents

โœ Scribed by M.A Rochester; G.O Hellawell; S.F Brewster; V.M Macaulay


Book ID
118645058
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
84 KB
Volume
2
Category
Article
ISSN
1569-9056

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Silencing of the type 1 insulin-like gro
โœ Zhiyuan Ma; Aiqiang Dong; Minjian Kong; Jianfang Qian ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› SP Versita ๐ŸŒ English โš– 688 KB

## Abstract The type 1 insulin-like growth factor receptor (IGF-1R), which is over-expressed or activated in many human cancers, including lung cancer, mediates cancer cell proliferation and metastasis. Several studies indicate that blocking IGF-1R expression can inhibit tumor cell proliferation an