## Overexpression of the ErbB2 and epidermal growth factor receptor (EGFR) tyrosine kinases is frequently observed in squamous cell carcinomas of the head and neck, and has been correlated with shorter overall survival. By immunoblot analysis, we have found EGFR and ErbB2 expression in 6 out of 6 e
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Silencing of the caspase-1 gene occurs in murine and human renal cancer cells and causes solid tumor growth in vivo
โ Scribed by Tetsuo Ueki; Takumi Takeuchi; Hiroaki Nishimatsu; Takahiro Kajiwara; Nobuo Moriyama; Yoshitaka Narita; Kazuki Kawabe; Keisuke Ueki; Tadaichi Kitamura
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- French
- Weight
- 396 KB
- Volume
- 91
- Category
- Article
- ISSN
- 0020-7136
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Germline mutations in the von Hippel-Lindau (VHL) disease tumor suppressor gene (TSG) convey a high risk of clear-cell renal-cell carcinoma (CC-RCC) and most sporadic CC-RCCs demonstrate somatic inactivation of the VHL TSG. However, the existence of further CC-RCC gatekeeper genes is implied by CC-R