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Silencing of CDK5 as potential therapy for Alzheimer’s disease

✍ Scribed by López-Tobón, Alejandro; Castro-Álvarez, John Fredy; Piedrahita, Diego; Boudreau, Ryan L.; Gallego-Gómez, Juan Carlos; Cardona-Gómez, Gloria Patricia


Book ID
111859125
Publisher
Walter de Gruyter GmbH & Co. KG
Year
2011
Tongue
English
Weight
278 KB
Volume
22
Category
Article
ISSN
0334-1763

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Alzheimer's disease (AD) represents the leading cause for senile dementia affecting more than 4 million people worldwide. AD patients display a triad of pathological features including brain atrophy caused by neuronal loss, h-amyloid plaque and neurofibrillary tangles. We previously show that Cyclin