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Significantly higher frequency of theMspI 2.2 kb allele of the Duchenne muscular dystrophy intragenic probe P-20 in the Chinese population

✍ Scribed by Jianjun Wei; Yishou Guo; Bingxi Chen; Yaping Yang


Book ID
104666254
Publisher
Springer
Year
1992
Tongue
English
Weight
313 KB
Volume
90
Category
Article
ISSN
0340-6717

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✦ Synopsis


The P-20 intragenic marker was used to test for restriction fragment length polymorphisms in unrelated Chinese patients with Duchenne or Becker muscular dystrophy or X-linked mental retardation. In addition to polymorphism at the 6.0/3.5 kb MspI allelic site, we found an independent and high frequency of polymorphism at the 2.2/1.8 kb site. This differs from results found with other populations.