The p21 protein inhibits cyclin-dependent kinases and mediates cell-cycle arrest and cell differentiation. It is induced by wild-type p53, but not by mutant p53. This study of 75 patients with endometrial carcinoma investigates the relationship between p21 expression and the functional status of p53
Significantly decreased P27 expression in endometrial carcinoma compared to complex hyperplasia with atypia (correlation with p53 expression)
✍ Scribed by Sevgiye Kacar Özkara; Aydin Corakci
- Book ID
- 105644928
- Publisher
- Springer Netherlands
- Year
- 2004
- Tongue
- English
- Weight
- 627 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1219-4956
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