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Significantly accelerated osteoblast cell growth on aligned TiO2 nanotubes

✍ Scribed by Seunghan Oh; Chiara Daraio; Li-Han Chen; Thomas R. Pisanic; Rita R. Fiñones; Sungho Jin

Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
630 KB
Volume
78A
Category
Article
ISSN
1549-3296

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✦ Synopsis

Abstract

Vertically aligned yet laterally spaced nanoscale TiO~2~ nanotubes have been grown on Ti by anodization, and the growth of MC3T3‐E1 osteoblast cells on such nanotubes has been investigated. The adhesion/propagation of the osteoblast is substantially improved by the topography of the TiO~2~ nanotubes with the filopodia of growing cells actually going into the nanotube pores, producing an interlocked cell structure. The presence of the nanotube structure induced a significant acceleration in the growth rate of osteoblast cells by as much as ∼300–400%. © 2006 Wiley Periodicals, Inc. J Biomed Mater Res, 2006

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