Significant effect of hepatitis C virus specific CTLs on viral clearance in patients with type C chronic hepatitis treated with antiviral agents
β Scribed by Shinichi Satake; Masahito Nagaki; Kiminori Kimura; Takafumi Naiki; Hideki Hayashi; Junichi Sugihara; Eiichi Tomita; Hisataka Moriwaki
- Book ID
- 118087915
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 381 KB
- Volume
- 38
- Category
- Article
- ISSN
- 1386-6346
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We quantified serum hepatitis C virus RNA titers and determined hepatltis C virus subtypes in chronic hepatitis C patients treated with interferon$ to investigate relationships among serum ALT response, serum hepatitis C virus titer and hepatitis C virus subtype. Of 146 chronic hepatitis C patients
Hepatitis C virus RNA as detected by reverse transcription and nested polymerase chain reaction was monitored in 16 patients with chronic hepatitis C treated with interferon. Hepatitis C virus R N A became undetectable after 4 to 8 wk of interferon administration in 13 of the 16 patients. During 6 m