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Significant deviations from Hardy–Weinberg equilibrium caused by low levels of microsatellite genotyping errors

✍ Scribed by PHILLIP A. MORIN; RICHARD G. LEDUC; FREDERICK I. ARCHER; KAREN K. MARTIEN; RYAN HUEBINGER; JOHN W. BICKHAM; BARBARA L. TAYLOR

Book ID: 118074014
Publisher: Wiley (Blackwell Publishing)
Year: 2009
Tongue: English
Weight: 96 KB
Volume: 9
Category: Article
ISSN: 1755-098X
DOI: 10.1111/j.1755-0998.2008.02502.x

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## Abstract Genotype error can greatly reduce the power of a genetic study. For family data, genotype error can be assessed by examining marker data for non‐Mendelian inconsistencies, closely linked markers for double recombination events, and consistency of duplicate genotypes. For case‐control da