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Significance of surgical margin on the prognosis of patients with Ewing's sarcoma: A report from the Cooperative Ewing's Sarcoma Study

✍ Scribed by Toshifumi Ozaki; Axel Hillmann; Christiane Hoffmann; Christian Rübe; Sebastian Blasius; Jürgen Dunst; Herbert Jürgens; Winfried Winkelmann

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 917 KB
Volume: 78
Category: Article
ISSN: 0008-543X
DOI: 10.1002/(sici)1097-0142(19960815)78:4<892::aid-cncr29>3.0.co;2-p

No coin nor oath required. For personal study only.

✦ Synopsis

BACKGROUND.

There is little information reg,arding an adequate surgical margin for local control of Ewing's sarcoma.

METHODS.

Two hundred and forty-four patients (PTS) with Ewing's sarcoma who were registered in the Cooperative Ewing's Sarcoma Studies underwent surgical treatment. Ninety-four PTS underwent definirive surgery (surgery alone), 131 PTS received postoperative irradiation, and 19 PTS received preoperative irradiation. The surgical margins were distributed as follows: radical, 29 PTS; wide, 148 PTS; marginal, 39 PTS; and intralesional, 28 PTS. The impact of the surgical margin on the treatment outcome of PTS was analyzed statistically.

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