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Significance of ROS in oxygen sensing in cell systems with sensitivity to physiological hypoxia

✍ Scribed by Constancio Gonzalez; Gloria Sanz-Alfayate; M.Teresa Agapito; Angela Gomez-Niño; Asunción Rocher; Ana Obeso


Book ID
117799893
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
275 KB
Volume
132
Category
Article
ISSN
1569-9048

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## Abstract Reduced oxygen tension (hypoxia) in the environment stimulates oxygen‐sensitive cells in the carotid body (CB). Upon exposure to hypoxia, the CB immediately triggers a reflexive physiological response, thereby increasing respiration. Adaptation to hypoxia involves changes in the express