Nuclear matrix (NM) plays roles of fundamental structural and functional significance as the site of replication, transcription, and RNA processing and transport, acting as an anchor or attachment site for a variety of enzymes and other proteins involved in these activities. We have previously docum
Significance of protein kinase CK2 nuclear signaling in neoplasia
โ Scribed by Khalil Ahmed; Alan T. Davis; Huamin Wang; Russell A. Faust; Shihui Yu; Sherif Tawfic
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 99 KB
- Volume
- 79
- Category
- Article
- ISSN
- 0730-2312
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Nuclear matrix (NM) appears to be an intranuclear locale for significant and dynamic association of the ubiquitous multifunctional messenger-independent serine/threonine protein kinase CK2 that has been implicated in growth control : J Cell Biochem 61:165-171]. We have examined the nature of the ass
Nuclear matrix (NM), a proteinaceous network of filaments, dictates nuclear morphology and the structure/function of DNA. Phosphorylation of NM proteins is a potential signal for regulating matrix functions. Histones also are intimately involved in DNA structure and transcription. Here, we report th
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