Five elderly depressed patients were treated with amitriptyline (AT) and nortriptyline (NT) in turn, in a crossover design. Steady-state plasma drug levels were compared with those calculated for eight healthy subjects of previous single-dose studies. Plasma clearances were on average about 2.5 time
Significance of monitoring plasma levels of amitriptyline, and its hydroxylated and desmethylated metabolites in prediction of the clinical outcome of depressive state
β Scribed by KAZUTAKA SHIMODA; SHIN YASUDA; SACHIYO MORITA; MORIKAZU SHIBASAKI; TOSHIYUKI SOMEYA; LEIF BERTILSSON; SABURO TAKAHASHI MD
- Book ID
- 108961498
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 687 KB
- Volume
- 51
- Category
- Article
- ISSN
- 1323-1316
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