Significance of Macrophage Migration Inhibitory Factor in Traumatic Condition and Effect of Hypertonic Saline
β Scribed by J.-Y. Kim; S.-H. Choi; Y.-H. Yoon; Y.-D. Cho; S.-M. Park; S.-W. Moon; S.-W. Lee; Y.-S. Hong; G.-S. Han; C. Han
- Book ID
- 119295186
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 40 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0736-4679
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## Abstract ## Objective To study the capacity of macrophage migration inhibitory factor (MIF) to regulate proliferation, apoptosis, and p53 in an animal model of rheumatoid arthritis (RA) and in fibroblastβlike synoviocytes (FLS) from humans with RA. ## Methods Antigenβinduced arthritis (AIA) w
## Abstract Macrophage migration inhibitory factor (MIF) is a protein that is overexpressed in many tumors, such as colon and prostate cancer, melanoma, and glioblastoma multiforme (GBM). In its function as a cytokine, MIF induces angiogenesis, promotes cell cycle progression, and inhibits apoptosi