Significance of bone marrow reticulin fibrosis in chronic lymphocytic leukemia at diagnosis
β Scribed by Tadmor, Tamar; Shvidel, Lev; Aviv, Ariel; Ruchlemer, Rosa; Bairey, Osnat; Yuklea, Mona; Herishanu, Yair; Braester, Andre; Levene, Naomi; Vernea, Fiona; Ben-Ezra, Jonathan; Bejar, Jacob; Polliack, Aaron
- Book ID
- 120155345
- Publisher
- John Wiley and Sons
- Year
- 2013
- Tongue
- English
- Weight
- 216 KB
- Volume
- 119
- Category
- Article
- ISSN
- 0008-543X
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## Abstract ## BACKGROUND Patients with chronic lymphocytic leukemia (CLL) that transforms to Richter syndrome (RS) frequently show atypical lymphocytes in bone marrow; however, a diagnosis of RS requires confirmation of the presence of sheets of large cells in bone marrow or lymph nodes. ## METH
Although bone marrow biopsy pattern (BMBP) has long been suggested to be an independent prognostic factor in chronic lymphocytic leukemia (CLL), conflicting reports continue to appear in the literature. To investigate this issue we retrospectively reviewed 70 CLL patients who had undergone bone marr