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Significance of Alpha-Fetoprotein and Des-γ-Carboxy Prothrombin in Patients with Hepatocellular Carcinoma Undergoing Hepatectomy

✍ Scribed by Kentaroh Yamamoto; Hiroshi Imamura; Yutaka Matsuyama; Kiyoshi Hasegawa; Yoshifumi Beck; Yasuhiko Sugawara; Masatoshi Makuuchi; Norihiro Kokudo

Book ID
111773168
Publisher
Springer
Year
2009
Tongue
English
Weight
490 KB
Volume
16
Category
Article
ISSN
1068-9265

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Clinical significance of simultaneous de
Clinical significance of simultaneous determinations of alpha-fetoprotein and des-gamma-carboxy prothrombin in monitoring recurrence in patients with hepatocellular carcinoma
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## BACKGROUND. Measurements of serum alpha-fetoprotein (AFP) concentration and plasma concentration of des-gamma-carboxy prothrombin (IICP) have been widely used for the early diagnosis of hepatocellular carcinoma (HCC). The two markers generally run parallel to each other. However, in our study, t

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Serum y-fetoprotein (AFP) and plasma des-y-carboxy prothrombin (DCP), a protein induced by vitamin K absence or antagonist I1 (PIVKA-11) levels, were measured in 197 patients with primary hepatocellular carcinoma (HCC). DCP levels were determined by conventional enzyme immunoassay kit (E-1023) and a