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Significance of acetylator phenotype in pharmacokinetics and adverse effects of procainamide

✍ Scribed by P. Ylitalo; R. Ruosteenoja; O. Leskinen; T. Metsä-Ketelä

Publisher
Springer
Year
1983
Tongue
English
Weight
646 KB
Volume
25
Category
Article
ISSN
0031-6970

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📜 SIMILAR VOLUMES

Acecainide pharmacokinetics in normal su
Acecainide pharmacokinetics in normal subjects of known acetylator phenotype
✍ James D. Coyle; Harisios Boudoulas; John J. Lima 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 630 KB

The purpose of this study was to determine the pharmacokinetics of acecainide (formerly N-acetylprocainamide) in six normal subjects of known acetylator phenotype. Three subjects were fast acetylators and three slow acetylators by sulfapyridine phenotyping criteria. Each subject received a 20-min, 3