Significance of the dog as ‘second anima
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L. M. Appelman; V. J. Feron
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Article
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1986
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John Wiley and Sons
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English
⚖ 618 KB
The toxicity data of 66 compounds adequately tested in the rat (as 'prime animal species') and in the dog (as 'second animal species') were studied to find out for how many of these compounds the study in dogs led to a lower 'no-toxic-effect level' (NTEL) than that found in the rat. From a quantitat