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Significance and confounders of peripheral DJ-1 and alpha-synuclein in Parkinson's disease

✍ Scribed by Min Shi; Cyrus P. Zabetian; Aneeka M. Hancock; Carmen Ginghina; Zhen Hong; Dora Yearout; Kathryn A. Chung; Joseph F. Quinn; Elaine R. Peskind; Douglas Galasko; Joseph Jankovic; James B. Leverenz; Jing Zhang

Book ID
116772367
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
164 KB
Volume
480
Category
Article
ISSN
0304-3940

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## Abstract Dementia is a common complication of Parkinson's disease (PD). It correlates significantly with the presence of cortical, limbic or nigral Lewy bodies, mainly constituted of alpha‐synuclein. Mutations of the alpha‐synuclein gene (SNCA) have been linked to rare familial forms of PD, whil