Recent Advances Have Carried Hepatology To New Frontiers. The Increasing Frequency With Which Steatotic And Cirrhotic Livers Undergo Surgery Obliges Liver Surgeons And Hepatologists To Understand The Molecular Mechanisms At Play In These Situations. Comprehension Of The Signaling Pathways Participating In Liver Regeneration, Hepatocellular Apoptosis And Ischemia/reperfusion Injury Is Essential. This Book Serves As A Source Of Information Of Facilitate The Reading Of The Literature And The Planning Of Trials. Translational Medicine Implies Knowledge Of The Molecular Targets Of Novel Therapeutic Strategies. It Is Our Goal To Stimulate More Research That Can Lead To More Exchanges Between The Laboratory, The Clinical Ward And The Operating Room.--book Jacket. Ch. 1. Hepatocytes / Giuliano Ramadori And Bernhard Saile -- Ch. 2. Signaling Pathways In Biliary Epithelial Cells / M. Fatima Leite And Michael H. Nathanson -- Ch. 3. Stellate Cells / Massimo Pinzani And Fabio Marra -- Ch. 4. Kupffer Cells / Manfred Bilzer And Alexander L. Gerbes -- Ch. 5. Hepatic Sinusoidal Endothelial Cells / Roman E. Perri And Vijay Shah -- Ch. 6. Extracellular Matrix / Alex Y. Hui And Scott L. Friedman -- Ch. 7. Il-6/gp130/stat3 / Rebecca Taub -- Ch. 8. Vascular Endothelial Growth Factor Signaling / David Semela And Jean-francois Dufour -- Ch. 9. Insulin Pathway / Miran Kim And Jack R. Wands -- Ch. 10. Nature And Function Of Hepatic Tumor Necrosis Factor-[alpha] Signaling / Jorn M. Schattenberg And Mark J. Czaja -- Ch. 11. The Fas/fasl Signaling Pathway / Maria Eugenia Guicciardi And Gregory J. Gores -- Ch. 12. Tgf-[beta] And The Smad Pathway In Liver Fibrogenesis / Axel M. Gressner, Steven Dooley And Ralf Weiskirchen -- Ch. 13. Interferon Signaling / Massimo Levrero -- Ch. 14. Cd14 And Toll Receptor / Allan Tsung And David A. Geller -- Ch. 15. The Wnt/[beta]-catenin Pathway / Satdarshan P. S. Monga And George K. Michalopoulos -- Ch. 16. Notch Signaling In Liver Disease / Sarbjit Nijjar And Alastair Strain -- Ch. 17. Extracellular Atp : Emerging Roles Of Purinergic Signaling / David Gatof And J. Gregory Fitz -- Ch. 18. Calcium Signaling / Lawrence D. Gaspers, Nicola Pierobon And Andrew P. Thomas -- Ch. 19. Map Kinase Pathways In The Control Of Hepatocyte Growth, Metabolism And Survival / Paul Dent -- Ch. 20. Pi3k, Pten And Akt / Thomas F. Franke And Daniel C. Berwick -- Ch. 21. Tor Signaling And Cell Growth Control / Lisa M. Ballou And Richard Z. Lin -- Ch. 22. Peroxisome Proliferator Activated Receptors / Raphael Genolet, Liliane Michalik And Walter Wahli -- Ch. 23. Transcriptional Response To Camp In The Liver / Maria Agnese Della Fazia, Giuseppe Servillo And Paolo Sassone-corsi -- Ch. 24. Heme Oxygenase System / Sei-ichiro Tsuchihashi, Ronald W. Busuttil And Jerzy W. Kupiec-weglinski -- Ch. 25. Nitric Oxide / Jose M. Prince And Timothy R. Billiar -- Ch. 26. Hypoxia-inducible Factor-1 Signaling System / Deborah Stroka And Daniel Candinas -- Ch. 27. Cyclins And Cdks In Liver Diseases / Siu Tim Cheung And Ronnie T. Poon -- Ch. 28. Telomeres And Telomerase : Distinctive Roles In Liver Regeneration, Cirrhosis And Carcinogenesis / Ande Satyanarayana And K. Lenhard Rudolph -- Ch. 29. Nk-[kappa]b / Tom Ludde And Christian Trautwein -- Ch. 30. Ceramide : Cell Regulation From A Lipid Perspective / Jeffrey A. Jones And Yusuf A. Hannun -- Ch. 31. Apoptosis And Mitochondria / Jose C. Fernandez-checa And Carmen Garcia-ruiz -- Ch. 32. Ubiquitin-proteasome Pathway In The Pathogenesis Of Liver Disease / Samuel W. French And Fawzia Bardag-gorce -- Ch. 33. Biological Clock In The Liver / Hitoshi Okamura -- Ch. 34. Pharmacogenomics Of Cholestatic Liver Disease / Christiane Pauli-magnus, Marie V. St-pierre And Peter J. Meier -- Ch. 35. Proteomics Of Signal Transduction Pathways / Oliver Kleiner And Jasminka Godovac-zimmermann. Jean-françois Dufour, Pierre-alain Clavien, Eds. ; Co-editors, Christian Trautwein, Rolf Graf. Includes Bibliographical References And Index.