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Signaling pathways activated by α1-adrenergic receptor subtypes in PC12 cells

✍ Scribed by Hongying Zhong; Deborah Lee; Anna Robeva; Kenneth P. Minneman

Book ID: 117172882
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 146 KB
Volume: 68
Category: Article
ISSN: 0024-3205
DOI: 10.1016/s0024-3205(01)01015-3

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## Abstract The effect of extracellular ATP was studied in PC12 cells, a neurosecretory line that releases ATP. The addition of micromolar concentrations of ATP to PC12 cells evoked a transient increase in the cytosolic free Ca^2+^ concentration ([Ca^2+^]~i~), as measured with the Ca^2+^‐dye fura 2