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Signaling inputs converge on nuclear effectors in TGF-β signaling

✍ Scribed by Peter ten Dijke; Kohei Miyazono; Carl-Henrik Heldin

Book ID
114328218
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
161 KB
Volume
25
Category
Article
ISSN
0968-0004

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TGFbeta signaling plays a central role in regulating a broad range of cellular responses in a variety of organisms. TGFbeta signaling from the cell membrane to the nucleus is mediated by the Smad family of proteins. During the past five years of intense investigation, key events in TGFbeta signaling