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Signaling from P2 nucleotide receptors to protein kinase cascades induced by CNS injury

✍ Scribed by Joseph T. Neary; Yuan Kang

Book ID
111640743
Publisher
Springer
Year
2005
Tongue
English
Weight
124 KB
Volume
31
Category
Article
ISSN
0893-7648

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## Abstract Activation of P2Y~2~ receptors by extracellular nucleotides has been shown to induce phenotypic differentiation of human promonocytic U937 cells that is associated with the inflammatory response. The P2Y~2~ receptor agonist, UTP, induced the phosphorylation of the MAP kinases MEK1/2 and