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Signaling by the Drosophila epidermal growth factor receptor pathway during development

โœ Scribed by Ben-Zion Shilo


Book ID
117099752
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
322 KB
Volume
284
Category
Article
ISSN
0014-4827

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Somatic mutations of epidermal growth fa
โœ Hisayuki Shigematsu; Adi F. Gazdar ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 540 KB

Somatic mutations in the tyrosine kinase (TK) domain of the epidermal growth factor receptor (EGFR) gene in lung cancers have generated enormous interest, because they predict for sensitivity to TK inhibitors (TKIs). While mutational status is of great importance in determining response to TKIs, it