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Signaling and proapoptotic functions of transformed cell-derived reactive oxygen species

✍ Scribed by G. Bauer


Book ID
117841340
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
352 KB
Volume
66
Category
Article
ISSN
0952-3278

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## Abstract The __ras__ proto‐oncogene is frequently mutated in human tumors and functions to constitutively stimulate signal transduction cascades, resulting in unchecked proliferation and malignant transformation. In certain cells, superoxide functions as a signal‐transduction messenger, mediatin