Signal transduction triggered by lipid A-like molecules in 70Z/3 pre-B lymphocyte tumor cells

Raf-independent and MEKK1-dependent acti

Raf-independent and MEKK1-dependent activation of NF-κB by hydrogen peroxide in 70Z/3 pre-B lymphocyte tumor cells

✍ Michael Lee; Woo Suk Koh 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 385 KB

We have previously demonstrated that hydrogen peroxide (H(2)O(2)) treatment of murine 70Z/3 pre-B lymphocytes inhibits the immune response to lipopolysaccharide by attenuating signaling through c-Jun N-terminal kinase (JNK) activation. In the present study, we further examined the signaling intermed