𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Signal transduction pathways mediating differential gene expression by IL-1 and TGFβ in chondrocytes

Book ID
114348798
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
110 KB
Volume
1
Category
Article
ISSN
1063-4584

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

TGF-β-induced expression of tissue inhib
TGF-β-induced expression of tissue inhibitor of metalloproteinases-3 gene in chondrocytes is mediated by extracellular signal-regulated kinase pathway and Sp1 transcription factor
✍ Hamid Yaqoob Qureshi; Judith Sylvester; Mohammed El Mabrouk; Muhammad Zafarullah 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 422 KB

## Abstract Transforming growth factor (TGF‐β1) is a potent inducer of chondrogenesis and stimulant of cartilage extracellular matrix (ECM) synthesis. Tissue inhibitor of metalloproteinases‐3 (TIMP‐3) is located in ECM and is the major inhibitor of matrix metalloproteinases (MMPs) and aggrecanase,

Up-regulation of tissue inhibitor of met
Up-regulation of tissue inhibitor of metalloproteinases-3 gene expression by TGF-β in articular chondrocytes is mediated by serine/threonine and tyrosine kinases
✍ Suming Su; John A. Dibattista; Yi Sun; Wen Qing Li; Muhammad Zafarullah 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 195 KB 👁 1 views

The balance between matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) regulates extracellular matrix turn-over in normal animal development, cancer cell metastasis, atherosclerotic plaque rupture and erosion of arthritic cartilage. Transforming growth factor beta (