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Signal transduction pathways as novel therapy targets in lung cancer

✍ Scribed by Reinmuth, Niels; Mesters, Rolf M.; Bieker, Ralf; Hoffknecht, Petra; Berdel, Wolfgang E.; Thomas, Michael

Book ID: 119319043
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 209 KB
Volume: 45
Category: Article
ISSN: 0169-5002
DOI: 10.1016/j.lungcan.2004.07.976

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Pathways involved in the transduction of biological signals within cells overlap with those involved in oncogenesis. Previous studies have identified a number of discrete disturbances of some elements of these pathways in human lung cancer cells, by virtue of the overexpression or the mutation of ce