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Signal transduction of receptor-mediated antiproliferative action of melatonin on human prostate epithelial cells involves dual activation of Gαs and Gαq proteins

✍ Scribed by Stephen Y. W. Shiu; Bo Pang; Chun W. Tam; Kwok-Ming Yao

Book ID
111264777
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
485 KB
Volume
49
Category
Article
ISSN
0742-3098

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✍ Gilad, Eli; Pick, Elah; Matzkin, Haim; Zisapel, Nava 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 221 KB 👁 3 views

BACKGROUND. Melatonin, the hormone secreted nocturnally by the pineal gland, binds to epithelial cells from the human benign prostate, and can reduce their growth and viability. The possible involvement of GTP binding proteins cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate