Signal Transduction in the Chronic Leukemias: Implications for Targeted Therapies
โ Scribed by Ahmed, Wesam; Van Etten, Richard A.
- Book ID
- 120046181
- Publisher
- Current Science Inc.
- Year
- 2013
- Tongue
- English
- Weight
- 306 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1558-8211
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A signiยฎcant number of human diseases can be attributed to defects in cellular signal transduction pathways. Large-scale proteomics projects now in progress seek to better deยฎne critical components of signal transduction networks, to enable more intelligent design of therapeutic agents that can spec
Cell division and apoptosis (programmed cell death) are the two major physiological processes which control the size of cell populations. Chronic lymphocytic leukaemia arises as a result of the clonal expansion of, usually B-, lymphocytes in which a dysregulation of apoptosis leads to prolonged cell