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Signal Transduction in Neuronal Migration: Roles of GTPase Activating Proteins and the Small GTPase Cdc42 in the Slit-Robo Pathway

โœ Scribed by Kit Wong; Xiu-Rong Ren; Yang-Zhong Huang; Yi Xie; Guofa Liu; Harumi Saito; Hao Tang; Leng Wen; Susann M. Brady-Kalnay; Lin Mei; Jane Y. Wu; Wen-Cheng Xiong; Yi Rao


Book ID
117268904
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
844 KB
Volume
107
Category
Article
ISSN
0092-8674

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Insulin-like growth factor-I (IGF-I) is an important anabolic growth factor in the maintenance of articular cartilage phenotypic expression. Chondrocyte morphology is also tightly linked to phenotype. The small G-protein Cdc42 plays a key role in regulation of cell morphology and phenotypic expressi