Signal transduction for interleukin-3-dependent leukotriene synthesis in normal human basophils: opposing role of tyrosine kinase and protein kinase C

Calphostin C induces AP1 synthesis and A

Calphostin C induces AP1 synthesis and AP1-dependent c-jun transactivation in normal human chondrocytes independent of protein kinase c-α inhibition: Possible role for c-jun N-terminal kinase

✍ Mengkun Zhang; Caroline Miller; Yulan He; Johanne Martel-Pelletier; Jean-Pierre 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 213 KB 👁 2 views

Activator protein-1 (AP1) regulates the promoter activity of a large number of genes associated with developmental, proliferative, inflammatory, and homeostatic processes in human connective tissue cells. Some of these genes (e.g., cyclooxygenase-2) are regulated by the protein kinase C (PKC) inhibi