Tumor necrosis factor-α initiated signal
✍
Renu G. Jain; Kelle D. Phelps; Phillip H. Pekala
📂
Article
📅
1999
🏛
John Wiley and Sons
🌐
English
⚖ 212 KB
Examination of the ability of tumor necrosis factor-␣ (TNF) to activate both the p44/42 and p38 MAP kinase cascades in fully differentiated 3T3-L1 adipocytes indicated a rapid MEK1/2-dependent activation of p44/42 MAP kinase. Use of the MEK1/2 inhibitor PD98059 indicated that this pathway at least i