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Signal peptidases in prokaryotes and eukaryotes - a new protease family

✍ Scribed by Dalbey, Ross E.; von Heijne, Gunnar


Book ID
122758285
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
611 KB
Volume
17
Category
Article
ISSN
0968-0004

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## Abstract A cysteine protease domain (CPD) has been recently discovered in a group of multifunctional, autoprocessing RTX toxins (MARTX) and __Clostridium difficile__ toxins A and B. These CPDs (referred to as CPDmartx) autocleave the toxins to release domains with toxic effects inside host cells